Page last updated: 2024-09-05

phenserine and 1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate

phenserine has been researched along with 1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate in 1 studies

Compound Research Comparison

Studies
(phenserine)
Trials
(phenserine)
Recent Studies (post-2010)
(phenserine)
Studies
(1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate)
Trials
(1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate)
Recent Studies (post-2010) (1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate)
88639702

Protein Interaction Comparison

ProteinTaxonomyphenserine (IC50)1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate (IC50)
CholinesteraseHomo sapiens (human)0.0194
AcetylcholinesteraseHomo sapiens (human)0.0194

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brossi, A; Flippen-Anderson, JL; Greig, NH; Hoffman, B; Holloway, HW; Yu, Q1

Other Studies

1 other study(ies) available for phenserine and 1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate

ArticleYear
Methyl analogues of the experimental Alzheimer drug phenserine: synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action.
    Journal of medicinal chemistry, 2001, Nov-22, Volume: 44, Issue:24

    Topics: Acetylcholinesterase; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Crystallography, X-Ray; Erythrocytes; Humans; Models, Molecular; Molecular Conformation; Physostigmine; Structure-Activity Relationship

2001